Research Associate II / Senior Research Associate, Microbiology & Functional Screening (100% ONSITE)

Full Time
Cambridge, MA 02139
Posted
Job description

Why Seres Therapeutics

Seres Therapeutics is a commercial-stage company developing novel microbiome therapeutics for serious diseases. Our lead program, VOWST™, obtained U.S. FDA approval in April 2023 as the first orally administered microbiota-based therapeutic to prevent recurrence of C. difficile infection (CDI) in adults following antibacterial treatment for recurrent CDI and is being commercialized in collaboration with Nestlé Health Science. We are evaluating SER-155 in a Phase 1b study in patients receiving allogeneic hematopoietic stem cell transplantation to reduce incidences of gastrointestinal infections, bloodstream infections, and graft-versus-host disease as well as additional preclinical stage programs targeting Infection Protection in medically compromised patients. We are also conducting research to inform further development of microbiome therapeutics for ulcerative colitis.

Position Summary

At Seres, we're leading the microbiome revolution — and our most revolutionary asset is our team. Their courage and deep commitment are what drives us on our mission to transform the lives of patients worldwide with revolutionary microbiome therapeutics.

Seres Therapeutics is seeking experienced and highly-motivated Research Associate II/ Research Associate to join our Microbiology and Functional Screening team to develop and implement high throughput functional screens that advance the company's Ecobiotic® therapeutics discovery programs in oncology, infectious and inflammatory diseases. As a member of the Microbiology and Functional Screening team, you will work intimately with research teams across the organization to translate critical insights in the field of the human microbiome into therapeutic leads. The successful candidate will be innovative, thrive in an intense and dynamic environment, and use his/her creative and imaginative problem solving skills to help bring new products to patients.

What You'll Do

  • Develop and implement in vitro functional assays to elucidate the mechanisms that microbes employ to modulate host immunity and inflammation to guide our preclinical pipeline of next generation microbial therapeutics
  • Apply such assays to functionally characterize proprietary microbial strains and identify therapeutic microbial compositions for pre-clinical projects
  • Troubleshoot protocols, critically analyze data, maintain detailed records and present screening results at project team meetings
  • Understand relevant scientific literature and interact with internal scientists to integrate biological screening efforts across therapeutic areas

What You'll Bring

  • Bachelors +2 years of related work experience or Masters in Microbiology, Immunology or related scientific field
  • Demonstrated experience in assay implementation, data organization and analysis
  • Experienced in mammalian cell culture and cell-based assays required
  • Experience with flow cytometry, cytokine and gene expression assays preferred but not required
  • Enthusiastic, proactive, flexible and detail-oriented
  • Must be able to work both independently and collaboratively in fast-paced development environment with competing priorities

Seres is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation, or any characteristic protected under applicable law.

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