The Gomez-Sequeira Lopez laboratory at the University of Virginia (UVA) School of Medicine, Department of Pediatrics seeks applicants for a Postdoctoral scholar to work in the mechanisms that determine the identity and fate of renin-expressing cells. The candidate will utilize epigenomic, single cell approaches, and lineage tracing strategies to understand the chromatin structure that determines the fate of renin cells during physiological changes in physiological status and disease. We are seeking candidates with experience in either epigenetic manipulation, imaging methodologies, working knowledge of cardiovascular and renal physiology and Medicine. The ideal candidate will have the ability to use bioinformatics approaches to understand genome-wide changes in chromatin structure during health and disease. A strong publication record is desirable. The candidate will work in a multidisciplinary and diverse team of investigators with access to cutting-edge conceptual and methodological approaches to understand how cells determine their identity. Please visit Circ Res. 2021 Apr 2; 128(7): 887-907.) and/or https://med.virginia.edu/pcen/investigators/r-ariel-gomez-m-d/

The UVA Department of Pediatrics and the UVA Children’s Hospital share a common goal to enhance the health and well-being of children and families through collaborative medical care, education of professionals dedicated to pediatric healthcare, breakthrough research that improves lives, leadership, and community service. For more information on the Department of Pediatrics, visit our website: https://med.virginia.edu/pediatrics/ .

The successful candidate will be expected to perform fundamental, laboratory-based research aimed at understanding the mechanisms that govern the fate of renin cells during health and disease. The candidate will isolate fluorescently labeled renin and other kidney cells from reporting mice and use them to map the transcriptome and chromatin states that determine the cell’s identity and function. In addition, the successful candidate will use in situ determination of the epigenomic and gene expression changes that occur during kidney maturation and disease

Minimum qualifications:

Qualified candidate must have a PhD or MD in a related field of study by appointment start date.

Preferred knowledge, skills and abilities:

Working knowledge of molecular techniques, including RNA/DNA isolation, in situ hybridization, histological techniques, cell isolation and culture, and an understanding of epigenomic techniques. A background in biochemistry and/or Medicine is highly desirable.

This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require traveling some distance to attend meetings, and programs.

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For additional information about the position, please contact R. Ariel Gomez, MD, Harrison Distinguished Professor of Pediatrics, rg@uvahealth.org

This is a restricted position, renewable on an annual basis, contingent on satisfactory performance and the continued availability of funding.

The University will perform background checks on all new hires prior to employment. The successful candidate will pass an education verification, criminal background check and pre-employment health screening. This is a full-time benefited position. For more information on the benefits at UVA, visit www.hr.virginia.edu/benefits. This position will sponsor applicants for work visas.

To Apply:
Process for Internal UVA Applicants: Please apply through your Workday Home page, search “Find Jobs”, and search for R0044927.

Process for External Applicants: Please visit UVA job board at https://uva.wd1.myworkdayjobs.com/UVAJobs and search for R0044927.

Complete an application online with the following documents:

• CV/Resume
• Cover Letter
• Contact information for three references/Letters of reference

Upload all materials into the resume submission field, multiple documents can be submitted into this one field. Alternatively, merge all documents into one PDF for submission. Applications that do not contain all required documents will not receive full consideration.

References may be completed via UVA’s standardized process Skill Survey. A total of five references will be requested via SkillSurvey during the final phase of the interview process.

For questions about the application process, please contact Christi Maguire Recruiting Specialist, at clm8sd@virginia.edu . Please reference R0044927.

For more information about UVA and the Charlottesville community please see http://www.virginia.edu/life/charlottesville and https://embarkcva.com/

Postdoctoral employment is temporary and is normally limited to an individual who has been awarded a Ph.D. or equivalent doctorate within the previous five years and who will be involved in full-time research or scholarship at the University. Employment as a Postdoctoral Research Associate is viewed as training and is preparatory for a full-time academic or research career, is supervised by a senior scholar, and allows the appointee to publish the results of his/her research or scholarship during the training period.

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The University of Virginia, i ncluding the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information.