About Stoke:

Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to addressing the underlying cause of severe diseases by upregulating protein expression with RNA-based medicines. Using the company’s proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore protein levels. Stoke’s first compound, STK-001 is in clinical testing for the treatment of Dravet syndrome, a severe and progressive genetic epilepsy. Dravet syndrome is one of many diseases caused by a haploinsufficiency, in which a loss of ~50% of normal protein levels leads to disease. Stoke is pursuing the development of STK-002 for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. Stoke’s initial focus is haploinsufficiencies and diseases of the central nervous system and the eye, although proof of concept has been demonstrated in other organs, tissues, and systems, supporting the company’s belief in the broad potential for its proprietary approach. Stoke is headquartered in Bedford, Massachusetts with offices in Cambridge, Massachusetts.

Position Purpose:

The Director, Program Management, in partnership with the Development Program Lead, will lead the Program Team to successfully shape and execute the project and drug development strategies, in early development. The Director, Program Management is accountable for the cross-functional planning and execution of one or more programs including definition of the operational strategy, management of timelines, quality, and risk assessment and mitigation. This position will report into Vice President, Portfolio & Alliance Management.

Key Responsibilities:

• 
  Partners with the Development Program Lead to lead a cross-functional matrix team in advancing programs across stages
• Accountable for creating and maintaining a cross-function development plan, timeline for each program and ensuring progress vs. plan
• Facilitates effective, science-based decisions including development of scenarios as needed, highlighting interdependencies and downstream impacts of strategic decisions
• Ensures all decisions are assessed as to their risks and impacts. Accountable for communication to team and stakeholders in a transparent and timely manner
• Ensure agreements for external collaborations are executed in accordance with contracts and lead alliance meetings, communications and decision making

Required Skills & Experience:

• Master’s degree in a scientific discipline
• Minimum of 5 years of industry experience in the pharmaceutical and biotechnology industries
• Minimum of 3 years of demonstrated competency in early phase drug development expertise with solid understanding of drug development pathway
• Demonstrated ability to lead matrix teams
• Experience in Alliance Management a plus
• Experience with commonly used project management tools including but not limited to Microsoft Project
• Strong communicator able to integrate and succinctly summarize the various parts of a project and effectively tailor messages to audience incl. senior leaders

At Stoke, we believe that innovation, the ability to successfully advance our ground-breaking science and having fun as a team are enhanced by being together in person, at least periodically. We allow for flexibility in work arrangements that balance individual’s needs and preferences with the needs of our business and our desire to foster a culture of collaboration and innovation.

Culture & Values:

Our values guide our work to deliver meaningful medicines for people who need them. We are committed to being true to ourselves, to our colleagues, and to the people with severe diseases who are counting on us. We embrace diversity within a unique culture that is defined by our values. Our employee-led Diversity, Inclusion, and Belonging Committee (DIB) underscores the importance of DIB to who we are and what we do.

To protect the health and well-being of our team, company policy requires that all employees and all new hires be fully vaccinated against COVID-19. By applying, you are confirming that, if hired, you can satisfy this express condition of employment. We will make reasonable accommodations available as may be required by applicable law. We will continue to evaluate our practices as we move forward.

Location(s):

Stoke operates sites in Bedford, MA, and Cambridge, MA. This position is a hybrid position with an office setting based in our Bedford, MA location.

Travel:

This position will require approximately 0% - 5% travel.

Benefits & Compensation:

At Stoke Therapeutics we are proud to offer comprehensive and competitive employee benefits, including medical, dental and vision insurance; life, long and short-term disability insurance; Paid Parental Leave; a 401K program with company match, unlimited vacation time, and an Employee Stock Purchase Program (ESPP). Compensation is market competitive for the industry and directly commensurate with experience. All positions are bonus and stock eligible.

Interested candidates: Please visit Stoke’s website to learn more and apply directly to the position listed on our Career Center:

https://www.stoketherapeutics.com/careers/

For more information, visit https://www.stoketherapeutics.com/ or follow the company on Twitter at @StokeTx.

All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status.

Stoke participates in E-Verify.